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Beilstein J. Org. Chem. 2017, 13, 1425–1429, doi:10.3762/bjoc.13.139
Graphical Abstract
Scheme 1: Synthesis of 3-substituted phthalides from substituted 2-formylbenzoic acids and β-keto acids.
Scheme 2: Substrate scope of the synthesis of 3-substituted phthalides. General reaction conditions: 1 (0.5 m...
Scheme 3: Possible mechanistic pathway.